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Year : 2012  |  Volume : 1  |  Issue : 2  |  Page : 107-111

Posterior reversible encephalopathy in a child with acute glomerulonepheritis and malrotated kidney

1 Department of Pediatrics, Faculty of Medicine, Zagazig University, Zagazig, Egypt
2 Department of Radiodiagnosis, Faculty of Medicine, Zagazig University, Zagazig, Egypt

Correspondence Address:
Doaa M Youssef
Department of Pediatrics, Faculty of Medicine, Zagazig University, Zagazig 44519
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2278-0521.100967

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Posterior reversible encephalopathy syndrome (PRES) is a clinico-radiological syndrome which is mostly associated with pre-eclampsia, autoimmune diseases, and cytotoxic medication. Our understanding of this disease is based mainly on case reports which identify causes, pattern, and prognosis, and the reports in children are not frequent. We report a case of acute glomerulonepheritis and PRES, which presented with generalized convulsions and loss of consciousness. On diffusion-weighted magnetic resonance imaging (MRI), the affected areas appeared hyperintense on both diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) maps, which is consistent with unrestricted diffusion in regions of PRES vasogenic edema. MR spectroscopy (MRS) revealed normal metabolite spectrum. Our case was completely reversible after blood pressure control. We conclude that PRES as a possibility should be considered in children with acute glomerulonepheritis with neurological findings, even with status epilepticus presentation, and that we can confirm our suspicion by MRI showing typical bilateral hypodense findings.

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