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  Indian J Med Microbiol
 

Figure 5: Intracellular pathways involved in growth hormone signaling. The activated Jak2 upon GH binding activates several intracellular substrates, most importantly signal transducer and activator of transcriptions 1, 3, and 5 (STATs), but it also activates other signaling pathways, such as mitogen-activated protein kinases (MAPKs) and phosphoinositol 3kinase (PI3K)

Figure 5: Intracellular pathways involved in growth hormone signaling. The activated Jak2 upon GH binding activates several intracellular substrates, most importantly signal transducer and activator of transcriptions 1, 3, and 5 (STATs), but it also activates other signaling pathways, such as mitogen-activated protein kinases (MAPKs) and phosphoinositol 3kinase (PI3K)